Je hanba, že se někdo dovede namáhat po mnoho let, aby se stal dobrým lékařem, obhájcem, učitelem nebo geometrem, a přitom není ochoten namáhat se příslušně dlouhý čas, aby se stal dobrým člověkem.

Galénos z Pergamu

Literatura

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Magazín Leonardo

Během transplantací implantátů orgánů hrozí vysoké riziko vzniku bakteriální infekce způsobené kontaminací z okolního prostředí. Bylo zjištěno, že jejich účinnost, především u stříbra, roste při vzniku komplexů nanočástic kovů s polymerními látkami jako je chitosan a kyselina hyaluronová. Inhibice replikace, strukturální změny buněčné stěny a intracelulárních a jaderných membrán, denaturace DNA a RNA jsou pozorovatelné i při působení nízkých koncentrací nanočástic stříbra. Escherichia coli O157: H7 a methicilin-rezistentní Staphylococcus aureus (MRSA) i při nízkých koncentracích SPNPs.
http://prehravac.rozhlas.cz/audio/3037025

Anti-Cancer Agents in Medicinal Chemistry

Being an active EABM of the Journal, we are pleased to provide you the free access of Volume 14, 2014 for the journal entitled “Anti-Cancer Agents in Medicinal Chemistry”. Kindly use the following link to access the account.
URL: http://www.eurekaselect.com/578/journal/anti-cancer-agents-medicinal-chemistry

Vážené dámy, vážení pánové,
dovoluji si Vás jako autory, kteří již dříve v podobných časopisech publikovali, informovat o novince na VUT v oblasti publikování v režimu Open Access. VUT v Brně se rozhodlo finančně podpořit publikační činnost svých autorů v režimu Open Access. Nově mohou autoři žádat o finanční příspěvek na pokrytí publikačního poplatku u časopisů z nakladatelství BioMed Central, Chemistry Central a Springer Open.

Na rok 2014 byla pro členství v BioMed Central alokována částka 4000 Euro. Přidělení dotace je podmíněno
• přijetím článku do některého z OA časopisů uvedeného alespoň v jedné z databází WOS nebo SCOPUS,
• OA časopis musí být plně otevřený ne tzv. hybridní OA časopisech (tzn. pouze některé články v časopise jsou OA)
• podpořený článek musí být uložen do repozitáře (Digitální knihovna VUT).
Více podrobnějších informací a odkaz na formulář k žádosti najdete na stránkách Dotace pro podporu publikování formou Open Access.

Prima ZOOM

http://zoom.iprima.cz/clanky/top-10-nejlepsi-animovane-fotky-z-vedy-za-rok-2013

Novinky z knihovny

Je otevřen přístup do database časopisů ACS z MENDELU přístupového bodu. Využijte tyto přístupy maximální míře. http://pubs.acs.org/

Current Protocols

V rámci řešení projektu MENDELU RESEARCH LIBRARY http://mereli.mendelu.cz/ byl na webových stránkách http://www.mendelu.cz/cz/sluzby_sz/icuk/databaze zpřístupněn nový elektronický informační zdroj a to Wiley Current Protocols
http://onlinelibrary.wiley.com/browse/publications?type=labprotocols. Jedná se o trvalý nákup Current Protocols publikovaných 2013-2017.

Byla prodloužena platnost Seznamu recenzovaných neimpaktovaných periodik ČR o jeden rok, tj. do 31. 12. 2013. V hodnocení pro rok 2013 budou bodovány výsledky typu Jrec dle oborů stanovených v platné Metodice pro léta 2013 až 2015.

Metalothionein information servis (16 T)

Differential transcytosis and toxicity of the hNGAL receptor ligands cadmium-metallothionein and cadmium-phytochelatin in colon-like Caco-2 cells: Implications for in vivo cadmium toxicity.
By: Langelueddecke, Christian; Lee, Wing-Kee; Thevenod, Frank
Toxicology letters Volume: 226 Issue: 2 Pages: 228-35 Published: 2014-Apr-21 (Epub 2014 Feb 08)

Tissue-specific copper accumulation, zinc levels, induction, and purification of metallothionein in freshwater crab Sinopotamon henanense exposed to subacute waterborne copper
By: Ma, Wenli; He, Yongji; Yan, Tao; et al.
ENVIRONMENTAL TOXICOLOGY Volume: 29 Issue: 4 Pages: 407-417 Published: APR 2014

Molecular evolution and functional divergence of the metallothionein gene family in vertebrates.
By: Seren, Nina; Glaberman, Scott; Carretero, Miguel A; et al.
Journal of molecular evolution Volume: 78 Issue: 3-4 Pages: 217-33 Published: 2014-Apr (Epub 2014 Feb 21)

Quantitation of Human Metallothionein Isoforms: A Family of Small, Highly Conserved, Cysteine-rich Proteins.
By: Mehus, Aaron A; Muhonen, Wallace W; Garrett, Scott H; et al.
Molecular & cellular proteomics : MCP Volume: 13 Issue: 4 Pages: 1020-33 Published: 2014-Apr (Epub 2014 Feb 03)

Metallothionein prevents cardiac pathological changes in diabetes by modulating nitration and inactivation of cardiac ATP synthase.
By: Cong, Weitao; Zhao, Ting; Zhu, Zhongxin; et al.
The Journal of nutritional biochemistry Volume: 25 Issue: 4 Pages: 463-74 Published: 2014-Apr (Epub 2014 Jan 28)

Zinc protects cyclophosphamide-induced testicular damage in rat: Involvement of metallothionein, tesmin and Nrf2.
By: Maremanda, Krishna Prahlad; Khan, Sabbir; Jena, Gopabandhu
Biochemical and biophysical research communications Volume: 445 Issue: 3 Pages: 591-6 Published: 2014-Mar-14 (Epub 2014 Feb 22)

Renal improvement by zinc in diabetic mice is associated with glucose metabolism signaling mediated by metallothionein and Akt, but not Akt2
By: Sun, Weixia; Wang, Yuehui; Miao, Xiao; et al.
FREE RADICAL BIOLOGY AND MEDICINE Volume: 68 Pages: 22-34 Published: MAR 2014

Metallothionein immunoexpression in selected benign epithelial odontogenic tumors.
By: Johann, Aline Cristina Batista Rodrigues; Caldeira, Patricia Carlos; Souto, Giovanna Ribeiro; et al.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology Volume: 43 Issue: 3 Pages: 177-82 Published: 2014-Mar (Epub 2013 Oct 11)

In vivo-folded metal-metallothionein3 complexes reveal the Cu-thionein rather than Zn-thionein character of this brain-specific mammalian metallothionein.
By: Artells, Ester; Palacios, Oscar; Capdevila, Merce; et al.
The FEBS journal Volume: 281 Issue: 6 Pages: 1659-78 Published: 2014-Mar (Epub 2014 Feb 19)

Zinc and low-dose of cadmium protect sertoli cells against toxic-dose of cadmium: The role of metallothionein
By: Kheradmand, Fatemeh; Nourmohammadi, Issa; Ahmadi-Faghih, Mohamad Amin; et al.
IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE Volume: 11 Issue: 6 Pages: 487-494 Published: JUN 2013

Influenza (16 T)

Identification of a highly conserved and surface exposed B-cell epitope on the nucleoprotein of influenza A virus.
By: Gui, Xun; Ge, Pinghui; Wang, Xuliang; et al.
Journal of medical virology Volume: 86 Issue: 6 Pages: 995-1002 Published: 2014-Jun (Epub 2013 Oct 17)

Multiplex electrical detection of avian influenza and human immunodeficiency virus with an underlap-embedded silicon nanowire field-effect transistor
By: Kim, Jee-Yeon; Ahn, Jae-Hyuk; Moon, Dong-Il; et al.
BIOSENSORS & BIOELECTRONICS Volume: 55 Pages: 162-167 Published: MAY 15 2014

Electrochemical immunosensor for detection of antibodies against influenza A virus H5N1 in hen serum
By: Jarocka, Urszula; Sawicka, Roza; Gora-Sochacka, Anna; et al.
BIOSENSORS & BIOELECTRONICS Volume: 55 Pages: 301-306 Published: MAY 15 2014

Structural Stability of Influenza A(H1N1)pdm09 Virus Hemagglutinins.
By: Yang, Hua; Chang, Jessie C; Guo, Zhu; et al.
Journal of virology Volume: 88 Issue: 9 Pages: 4828-38 Published: 2014-May (Epub 2014 Feb 12)

Viruses associated with influenza-like-illnesses in Papua New Guinea, 2010
By: Kono, Jacinta; Jonduo, Marinjho H.; Omena, Matthew; et al.
JOURNAL OF MEDICAL VIROLOGY Volume: 86 Issue: 5 Pages: 899-904 Published: MAY 2014

1,2,3-Triazole-containing derivatives of rupestonic acid: Click-chemical synthesis and antiviral activities against influenza viruses.
By: He, Yao-Wu; Dong, Chang-Zhi; Zhao, Jiang-Yu; et al.
European journal of medicinal chemistry Volume: 76 Pages: 245-55 Published: 2014-Apr-9 (Epub 2014 Feb 11)

The co-pathogenesis of influenza viruses with bacteria in the lung
By: McCullers, Jonathan A.
NATURE REVIEWS MICROBIOLOGY Volume: 12 Issue: 4 Pages: 252-262 Published: APR 2014

Estimating the Fitness Advantage Conferred by Permissive Neuraminidase Mutations in Recent Oseltamivir-Resistant A(H1N1)pdm09 Influenza Viruses.
By: Butler, Jeff; Hooper, Kathryn A; Petrie, Stephen; et al.
PLoS pathogens Volume: 10 Issue: 4 Pages: e1004065 Published: 2014-Apr

IFITM3 Restricts Influenza A Virus Entry by Blocking the Formation of Fusion Pores following Virus-Endosome Hemifusion.
By: Desai, Tanay M; Marin, Mariana; Chin, Christopher R; et al.
PLoS pathogens Volume: 10 Issue: 4 Pages: e1004048 Published: 2014-Apr

Alveolar Macrophages Are Essential for Protection from Respiratory Failure and Associated Morbidity following Influenza Virus Infection.
By: Schneider, Christoph; Nobs, Samuel P; Heer, Alex K; et al.
PLoS pathogens Volume: 10 Issue: 4 Pages: e1004053 Published: 2014-Apr

Chitosan nanoparticle encapsulated hemagglutinin-split influenza virus mucosal vaccine.
By: Sawaengsak, Chompoonuch; Mori, Yasuko; Yamanishi, Koichi; et al.
AAPS PharmSciTech Volume: 15 Issue: 2 Pages: 317-25 Published: 2014-Apr (Epub 2013 Dec 17)

The Influenza A Virus Protein NS1 Displays Structural Polymorphism.
By: Carrillo, Berenice; Choi, Jae-Mun; Bornholdt, Zachary A; et al.
Journal of virology Volume: 88 Issue: 8 Pages: 4113-22 Published: 2014-Apr (Epub 2014 Jan 29)

Immune Escape Mutants of Highly Pathogenic Avian Influenza H5N1 Selected Using Polyclonal Sera: Identification of Key Amino Acids in the HA Protein
By: Sitaras, Ioannis; Kalthoff, Donata; Beer, Martin; et al.
PLOS ONE Volume: 9 Issue: 2 Article Number: e84628 Published: FEB 25 2014

Fragile X mental retardation protein stimulates ribonucleoprotein assembly of influenza A virus
By: Zhou, Zhuo; Cao, Mengmeng; Guo, Yang; et al.
NATURE COMMUNICATIONS Volume: 5 Pages: 3259-3259 Published: FEB 2014

Effect of the PB2 and M Genes on the Replication of H6 Influenza Virus in Chickens.
By: Ozaki, Hiroichi; Guan, Yi; Peiris, Malik; et al.
Influenza research and treatment Volume: 2014 Pages: 547839 Published: 2014 (Epub 2014 Feb 18)

Information servis (16 T)

Int. J. Mol. Sci. Proteins and Protein-Ligand Interactions 30.1.2014
http://www.mdpi.com/journal/ijms/special_issues/proteins_protein-ligand_interactions

Int. J. Mol. Sci. Antimicrobial Polymers 31.6.2014
http://www.mdpi.com/journal/ijms/special_issues/antimicrobial-polymers

Int. J. Mol. Sci. Identification and Roles of the Structure of DNA 30.5.2014
http://www.mdpi.com/journal/ijms/special_issues/Structure-DNA

Int. J. Mol. Sci. Bioactive Nanoparticles 2014 31.10.2014
http://www.mdpi.com/journal/ijms/special_issues/bioactive_nanoparticles_2014

Int. J. Mol. Sci. Mass Spectrometry Application in Biology 20.03.2014
http://www.mdpi.com/journal/ijms/special_issues/mass-spectrometry

Int. J. Mol. Sci. Advances in Proteomic Research 2014 10.04.2014
http://www.mdpi.com/journal/ijms/special_issues/proteomic-research-2014

Int. J. Mol. Sci. Human Single Nucleotide Polymorphisms and Disease Diagnostics 30.4.2014
http://www.mdpi.com/journal/ijms/special_issues/disease-diagnostics

Int. J. Mol. Sci. Molecular Research in Urology 2014 15.6.2014
http://www.mdpi.com/journal/ijms/special_issues/mol_res_uro_2014

Int. J. Mol. Sci. Bioactive Nanoparticles 2014 31.10.2014
http://www.mdpi.com/journal/ijms/special_issues/bioactive_nanoparticles_2014

Int. J. Env. Res. Publ. Health Endocrine Disruptors and Human Health 31.5.2014
http://www.mdpi.com/journal/ijerph/special_issues/endocrine_disruptors

Sensors Amperometric Biosensors 31.10.2014
http://www.mdpi.com/journal/sensors/special_issues/amperometric-biosensors

Sensors Intracellular Sensing 30.06.2014
http://www.mdpi.com/journal/sensors/special_issues/intracellular_sensing

Sensors On-Chip Sensors 15.6.2014
http://www.mdpi.com/journal/sensors/special_issues/on-chip-sensors

Sensors Biomedical Sensors and Systems 15.04.2014
http://www.mdpi.com/journal/sensors/special_issues/biomedical-sensors

Sensors Nanopore Sensors: Fabrications, Properties and Applications 15.05.2014
http://www.mdpi.com/journal/sensors/special_issues/nanopore-sensors

Sensors Live Cell-Based Sensors with Receptors 15.05.2014
http://www.mdpi.com/journal/sensors/special_issues/cell_sens_receptor

Sensors Immunosensors 2014 31.05.2014
http://www.mdpi.com/journal/sensors/special_issues/immunosensors_2014

Molecules Dendrimers in Medicine and Biotechnology 15.6.2014
http://www.mdpi.com/journal/molecules/special_issues/dendrimers-in-medicine

Molecules miRNAs as Probes to Monitor Cancer and Neurodegenerative Disorders 28.2.2014
http://www.mdpi.com/journal/molecules/special_issues/neurodegenerative-disorders

Molecules Practical Applications of Metal Complexes 15.6.2014
http://www.mdpi.com/journal/molecules/special_issues/metal-complexes

Molecules Fluorescent Probes 30.4.2014
http://www.mdpi.com/journal/molecules/special_issues/fluorescent-probes

Molecules Bio and Nanomaterials Based on Fe3O4 30.5.2014
http://www.mdpi.com/journal/molecules/special_issues/Fe3O4

Molecules Dendrimers in Medicine and Biotechnology 15.6.2014
http://www.mdpi.com/journal/molecules/special_issues/dendrimers-in-medicine

Molecules Peptide Chemistry 31.7.2014
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Molecules Delivery Systems of Anticancer Agents 31.7.2014
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Molecules Novel Drug Candidates for Anticancer Therapy: Design, Preliminary Evaluations, and Further Developments 15.10.2014
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Metallomics Zinc in the Biosciences 28.2.2014
http://blogs.rsc.org/mt/2013/10/03/themed-issue-on-zinc-in-the-biosciences-submissions-open/

Materials Advances nanomaterials for biosensors 31.3.2014
http://www.mdpi.com/journal/materials/special_issues/advanced-nanomaterials

Viruses Viral-bacterial Interactions 31.5.2014
http://www.mdpi.com/journal/viruses/special_issues/viral-bacterial_interactions

Viruses HIV Drug Resistance 31.05.2014
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Viruses Feature Papers Prions 30.04.2014
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