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Protestors from two anti-GMO groups, KMB and Sikwal-GMO, yesterday vandalized a field of genetically modified (GM) "golden rice" in the Bicol region of the Philippines.
GMA News TV channel in the Philippines showed dozens of young men and women tearing down fences, swarming over a rice field, and uprooting stalks. "I am outraged," says Ingo Potrykus, a plant biologist, now retired, who was one of the researchers that originally created the rice strain. The rice was just weeks away from being harvested, he says. "Important data were to be collected from that field trial, and this can set us back months."
Golden rice is engineered to carry two foreign genes—one bacterial and another from maize—that together produce beta carotene, a precursor of vitamin A that gives the rice grains their characteristic yellow hue. Scientists hope distribution of the modified rice can make inroads against vitamin A deficiency, which can lead to blindness and makes people more susceptible to infectious diseases. The deficiency affects approximately 1.7 million children aged 6 months to 5 years in the Philippines alone, according to the International Rice Research Institute. The vandalized field was one of five involved in golden rice trials in the Philippines aiming to show that "the plants are suitable for cultivation and would give farmers a good crop, and to assess any environmental impact they might have," says Robert Zeigler, director general of the International Rice Research Institute. The grain harvested from the plants is also needed for studies assessing whether the beta carotene in the rice is absorbed and converted into vitamin A in vitamin A-deficient people. Golden rice could be deemed safe by regulatory authorities as early as the end of this year—but the efficacy trials, which could take another 18 months, have to be finished before the Philippine government makes the final decision about approving the crop. That's the timeline if the remaining field sites are unmolested, Zeigler says.
The Philippines’ Agriculture Department plans to step up security at the trial sites. In Zeigler’s view, the vandals are unfairly attacking the public sector project as if it is a multinational company producing GM plants for profit. They “are condemning this technology by association," he says.

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Metalothionein information servis (31 T)

Title: Using biomarkers in an evolutionary context: Lessons from the analysis of biological responses of oligochaete annelids to metal exposure
Author(s): Pauwels, Maxime; Frerot, Helene; Souleman, Dima; et al.
Source: ENVIRONMENTAL POLLUTION Volume: 179 Pages: 343-350 DOI: 10.1016/j.envpol.2013.05.005 Published: AUG 2013

Title: The protective effects of metallothionein-I/II against cerebral ischemia and reperfusion injury
Author(s): Feng, Min; Huang, Chang; Guo, Jia-bin; et al.
Source: ACTA PHARMACOLOGICA SINICA Volume: 34 Supplement: S Pages: 103-103 Published: JUL 2013

Title: Effect of intravenously injected zinc on tissue zinc and metallothionein gene expression of broilers
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Source: BRITISH POULTRY SCIENCE Volume: 54 Issue: 3 Pages: 381-390 DOI: 10.1080/00071668.2013.787158 Published: JUN 1 2013

Title: Evaluation of serum metallothionein-1, selenium, zinc, and copper in Ghanaian type 2 diabetes mellitus patients
Author(s): Asare, George Awuku; Osae, Shiloh; Nortey, Ezekiel Nii Noye; et al.
Source: INTERNATIONAL JOURNAL OF DIABETES IN DEVELOPING COUNTRIES Volume: 33 Issue: 2 Pages: 86-95 DOI: 10.1007/s13410-013-0111-9 Published: JUN 2013

Title: The Effects of Cadmium Exposure on the Oxidative State and Cell Death in the Gill of Freshwater Crab Sinopotamon henanense
Author(s): Wang, Jinxiang; Zhang, Pingping; Shen, Qingqing; et al.
Source: PLOS ONE Volume: 8 Issue: 5 Article Number: e64020 DOI: 10.1371/journal.pone.0064020 Published: MAY 30 2013

Title: Heterologous Expression and Metal-Binding Characterization of a Type 1 Metallothionein Isoform (OsMTI-1b) from Rice (Oryza sativa)
Author(s): Nezhad, Rezvan Mohammadi; Shahpiri, Azar; Mirlohi, Aghafakhr
Source: PROTEIN JOURNAL Volume: 32 Issue: 2 Pages: 131-137 DOI: 10.1007/s10930-013-9469-2 Published: FEB 2013

Title: Characterization of mercury-containing protein in human plasma
Author(s): Yun, Zhaojun; Li, Lu; Liu, Lihong; et al.
Source: METALLOMICS Volume: 5 Issue: 7 Pages: 821-827 DOI: 10.1039/c3mt00036b Published: 2013

Title: Chemical interactions of mercury species and some transition and noble metals towards metallothionein (Zn7MT-2) evaluated using SEC/ICP-MS, RP-HPLC/ESI-MS and MALDI-TOF-MS
Author(s): Xu, Ming; Yang, Limin; Wang, Qiuquan
Source: METALLOMICS Volume: 5 Issue: 7 Pages: 855-860 DOI: 10.1039/c3mt00016h Published: 2013

Title: Selenoprotein P and selenoprotein M block Zn2+-mediated A beta(42) aggregation and toxicity
Author(s): Du, Xiubo; Li, Haiping; Wang, Zhi; et al.
Source: METALLOMICS Volume: 5 Issue: 7 Pages: 861-870 DOI: 10.1039/c3mt20282h Published: 2013

Influenza (31 T)

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Source: PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES Volume: 280 Issue: 1766 Article Number: 20131345 DOI: 10.1098/rspb.2013.1345 Published: SEP 7 2013

Title: A novel canine influenza H3N2 virus isolated from cats in an animal shelter
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Source: VETERINARY MICROBIOLOGY Volume: 165 Issue: 3-4 Pages: 281-286 DOI: 10.1016/j.vetmic.2013.03.021 Published: AUG 30 2013

Title: Genetic variation and phylogenetic analysis of hemagglutinin genes of H9 avian influenza viruses isolated in China during 2010-2012
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Source: VETERINARY MICROBIOLOGY Volume: 165 Issue: 3-4 Pages: 312-318 DOI: 10.1016/j.vetmic.2013.04.005 Published: AUG 30 2013

Title: Differences in the detection of highly pathogenic avian influenza H5N1 virus in feather samples from 4-week-old and 24-week-old infected Pekin ducks (Anas platyrhynchos var. domestica)
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Source: VETERINARY MICROBIOLOGY Volume: 165 Issue: 3-4 Pages: 443-447 DOI: 10.1016/j.vetmic.2013.03.019 Published: AUG 30 2013

Title: Identification and Analysis of the First 2009 Pandemic H1N1 Influenza Virus from US Feral Swine
Author(s): Clavijo, A.; Nikooienejad, A.; Esfahani, M. S.; et al.
Source: ZOONOSES AND PUBLIC HEALTH Volume: 60 Issue: 5 Pages: 327-335 DOI: 10.1111/zph.12006 Published: AUG 2013

Title: Swine, human or avian influenza viruses differentially activates porcine dendritic cells cytokine profile
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Source: VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY Volume: 154 Issue: 1-2 Pages: 25-35 DOI: 10.1016/j.vetimm.2013.04.004 Published: JUL 15 2013

Title: Influenza - Time to Target the Host?
Author(s): Baillie, J. Kenneth; Digard, Paul
Source: NEW ENGLAND JOURNAL OF MEDICINE Volume: 369 Issue: 2 Pages: 191-193 DOI: 10.1056/NEJMcibr1304414 Published: JUL 11 2013

Title: Virus-like particle vaccine protects against H3N2 canine influenza virus in dog
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Title: Lineage Structure of the Human Antibody Repertoire in Response to Influenza Vaccination (vol 5, 193er8, 2013)
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Source: SCIENCE TRANSLATIONAL MEDICINE Volume: 5 Issue: 193 Article Number: 193er8 DOI: 10.1126/scitranslmed.3006834 Published: JUL

Title: An M2e-based synthetic peptide vaccine for influenza A virus confers heterosubtypic protection from lethal virus challenge
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Source: VIROLOGY JOURNAL Volume: 10 Article Number: 227 DOI: 10.1186/1743-422X-10-227 Published: JUL 9 2013

Title: Lessons from Lipids in the Fight against Influenza
Author(s): Garcia-Sastre, Adolfo
Source: CELL Volume: 154 Issue: 1 Pages: 22-23 DOI: 10.1016/j.cell.2013.06.024 Published: JUL 3 2013

Title: A Systems Analysis Identifies a Feedforward Inflammatory Circuit Leading to Lethal Influenza Infection
Author(s): Brandes, Marlene; Klauschen, Frederick; Kuchen, Stefan; et al.
Source: CELL Volume: 154 Issue: 1 Pages: 197-212 DOI: 10.1016/j.cell.2013.06.013 Published: JUL 3 2013
Times Cited: 0 (from Web of Science)

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Title: Effects of Jin Chai antiviral capsule in vivo approach of influenza virus infection through inhibition of virus induced NF-kappa B activation
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Source: ACTA PHARMACOLOGICA SINICA Volume: 34 Supplement: S Pages: 35-36 Published: JUL 2013

Title: A potential drug target CLK1 from host cell for anti-influenza drug discovery
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Source: ACTA PHARMACOLOGICA SINICA Volume: 34 Supplement: S Pages: 45-45 Published: JUL 2013

Title: In vitro anti-influenza virus activity of stilbene derivatives
Author(s): Li, Chao; Liu, Ai-lin; Du, Guan-hua
Source: ACTA PHARMACOLOGICA SINICA Volume: 34 Supplement: S Pages: 151-151 Published: JUL 2013

Title: Adamantane and neuraminidase inhibitor resistance among circulating human influenza A viruses in Cuba during 2006-2010
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Title: Broad protection against influenza infection by vectored immunoprophylaxis in mice
Author(s): Balazs, Alejandro B.; Bloom, Jesse D.; Hong, Christin M.; et al.
Source: NATURE BIOTECHNOLOGY Volume: 31 Issue: 7 Pages: 647-U110 DOI: 10.1038/nbt.2618 Published: JUL 2013

Title: The duck genome and transcriptome provide insight into an avian influenza virus reservoir species
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Source: NATURE GENETICS Volume: 45 Issue: 7 Pages: 776-U97 DOI: 10.1038/ng.2657 Published: JUL 2013

Title: Glycan Receptor Binding of the Influenza A Virus H7N9 Hemagglutinin
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Source: CELL Volume: 153 Issue: 7 Pages: 1486-1493 DOI: 10.1016/j.cell.2013.05.034 Published: JUN 20 2013

Title: Cellular RNA Binding Proteins NS1-BP and hnRNP K Regulate Influenza A Virus RNA Splicing
Author(s): Tsai, Pei-Ling; Chiou, Ni-Ting; Kuss, Sharon; et al.
Source: PLOS PATHOGENS Volume: 9 Issue: 6 Article Number: e1003460 DOI: 10.1371/journal.ppat.1003460 Published: JUN 2013

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