Modern imaging techniques

Zuzana Kratka, Iva Blazkova, Marketa Vaculovicova, Vojtech Adam, Rene Kizek


Quantum dots are small semiconductor nanoparticles with great fluorescence properties including broad excitation and narrow emission spectra, high quantum yields, high photostability, possibility to be synthesize in a wide variety of colors and suitability for functionalization they are new member of a family of fluorescent labels. Due to their unique optical and electrochemical properties they have proven to be very beneficial not only for biomolecule labeling for in vitro analysis but also for in vivo applications. This review article is focused on the current imaging methods. The usage of fluorescence methods in diagnosis is discussed. This paper concerns to the fluorescence imaging and possibilities of the usage of quantum dots in in vivo imaging.

1. Medintz I. L., Uyeda H. T., Goldman E. R., Mattoussi H.: Nature Materials, 4, 435 (2005).
2. Walling M. A., Novak J. A., Shepard J. R. E.: International Journal of Molecular Sciences, 10, 441 (2009).
3. Bruchez M., Moronne M., Gin P., Weiss S., Alivisatos A. P.: Science, 281, 2013 (1998).
4. Resch-Genger U., Grabolle M., Cavaliere-Jaricot S., Nitschke R., Nann T.: Nature Methods, 5, 763 (2008).
5. Drbohlavova J., Adam V., Kizek R., Hubalek J.: International Journal of Molecular Sciences, 10, 656 (2009).
6. Leblond F., Davis S. C., Valdes P. A., Pogue B. W.: Journal of Photochemistry and Photobiology B-Biology, 98, 77 (2010).
7. Mohammadi-Gheidari A., Kruit P.: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 645, 60 (2011).
8. Yoshimura N.: Historical Evolution toward Achieving Ultrahigh Vacuum in Jeol Electron Microscopes, 1 (2014).
9. de Pablo P. J.: Single Molecule Analysis: Methods and Protocols, 783, 197 (2011).
10. Hughes J., Velká všeobecná encyklopedie, Svojtka & Co., s.r.o., 2002.
11. Seidl Z. V. M., Magnetická rezonance hlavy, mozku a páteře, 2006.
12. Ter-Pogossian M. M., Phelps M. E., Hoffman E. J., Mullani N. A., Positron-emission transaxial tomograph for nuclear imaging (PETT), 1975.
13. Phelps M. E., Hoffman E. J., Mullani N. A., Ter-Pogossian M. M.: Journal of Nuclear Medicine, 16, 210 (1975).
14. Fercher A. F., Mengedoht K., Werner W.: Optics Letters, 13, 186 (1988).
15. Ntziachristos V., Bremer C., Weissleder R.: European Radiology, 13, 195 (2003).
16. Tan W. H., Wang K. M., He X. X., Zhao X. J., Drake T., Wang L., Bagwe R. P.: Medicinal Research Reviews, 24, 621 (2004).
17. Chen H., Wang Y., Xu J., Ji J., Zhang J., Hu Y., Gu Y.: Journal of Fluorescence, 18, 801 (2008).
18. Fišar Z.: Multimediální podpora výuky klinických a zdravotnických oborů :: Portál 1. lékařské fakulty Karlovy Univerzity v Praze [online], (2012).
19. Gao J. H., Chen K., Xie R. G., Xie J., Yan Y. J., Cheng Z., Peng X. G., Chen X. Y.: Bioconjugate Chemistry, 21, 604 (2010).
20. Ghaderi S., Ramesh B., Seifalian A. M.: Journal of Drug Targeting, 19, 475 (2011).
21. Algar W. R., Tavares A. J., Krull U. J.: Analytica Chimica Acta, 673, 1 (2010).
22. Hoshino A., Hanada S., Yamamoto K.: Archives of Toxicology, 85, 707 (2011).
23. Mohs A. M., Duan H., Kairdolf B. A., Smith A. M., Nie S.: Nano Research, 2, 500 (2009).
24. Smith A. M., Duan H., Mohs A. M., Nie S.: Advanced Drug Delivery Reviews, 60, 1226 (2008).
25. Hlavacek A., Skladal P.: Chemicke Listy, 105, 611 (2011).
26. Choi A. O., Brown S. E., Szyf M., Maysinger D.: Journal of Molecular Medicine-Jmm, 86, 291 (2008).
27. Yong K.-T.: Nanotechnology, 20, (2009).

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