Study of the interaction of quantum dots with tumor cells by fluorescence microscopy

Iva Blazkova, Pavel Kopel, Marketa Vaculovicova, Vojtech Adam, Rene Kizek


This review is aimed on the interaction of quantum dots with tumor cells by fluorescence microscopy, we analyze the possibilities of the usage of QDs in tumor cell detection and visualization by fluorescence microscopy. QDs are fluorescent nanoparticles with good fluorescence properties. Specifically modified QDs can be targeted to the tumor tissue. QDs can be modified by antibodies, proteins, carbohydrates etc. For the use of QDs in biological applications, their solubility in water, stability and biocompatibility is important. Fluorescence microscopy is a good tool to observe interaction of QDs with cells and enable direct differentiation of normal and tumor cells.

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