Fluorescence imaging for specific analysis of cancer cells

Cancer is life-threatening disease, which causes nearly 7 million deaths every year worldwide and represents around 1 trillion dollars economic loss [1,2]. Cancer presents 25% of death caused in the developed countries [3]. But due to an early diagnosis and effective treatment, the mortality caused by this disease decreases and survival time increases [4]. The risk of dying from cancer decreased by 20% between 1991 and 2010 [3]. The cancer is diagnosed in the every third woman and every second man in the United States [5]. Cancer mortality in Czech Republic is about 20% [6,7]. Death rates continue to decline for all 4 major cancer sites (lung, colorectal, breast, and prostate), with lung cancer accounting for almost 40% of the total decline in men and breast cancer accounting for 34% of the total decline in women [4]. The most common causes of death are cancers of the lung, followed by colorectal, breast and stomach [7]. Early detection of cancer can significantly impact survival of cancer patients, so the regular screening is highly recommended [8-10].

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