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Každý, kdo se přestane učit, je starý, ať je mu 20 nebo 80. Každý, kdo se stále učí, zůstává mladý. Je nejlepší v životě zůstat mladý.

Henry Ford

Tisková zpráva
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Zprávy z laboratoře / Laboratory information

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Picture of the week

Pravidelný seminář (29 T) Rosa canina, Dog Rose, is the cheapest and most commonly used wild rose for use as a country hedging plants. This hardy native bush will grow pretty much anywhere except very wet sites. Rosa canina is good for hedges up to about 3 metres high.


Pravidelný seminář (29 T) Nové dva evropské projekty vstupují do naší laboratoře. ID 120 Green Learning Network http://www.greenlearningnetwork.eu/ a projekt ID 134 Young Innovation brokers for Visegrad countries http://visegradfund.org/. Oba projekty jsou primárně zaměřeny na networking mezi evropskými státy.


Pravidelný seminář (29 T)


Automated Voltammetric Determination of Lead(II) Ions Using Sensor Array
Pravidelný seminář (40 T)
Development of modern analytical instruments has been leading to miniaturization. This trend is mainly supported by expansion of biosensors applications. Electrochemistry, as one part of group of analytical methods, is moving in this range too. These sensitive analytical methods have been suggested for detection of various analytes including metal ions [1-6], peptides [7-11], proteins [12-24], nucleic acids [25-36] and others [37,38]. The classic electrochemical instrumentation is consisted of potentiostat/galvanostat with electrochemical cell including three electrodes (working, reference and auxiliary). As the working electrode, hanging mercury drop electrode (HMDE) is commonly used [39]. HMDE can be also modified by biologically active substances to improve sensitivity or selectivity of heavy metal ions detection [38,40-44]. Due to adverse effects of Hg(II) and many restrictions for usage of this metal, carbon electrodes has been found as an alternative [45-53]. As we mentioned above, the trend of the analytical techniques is to miniaturize the whole instrument, in which carbon electrodes have much more advantages compared to HMDE [54-57].

Již před 10 lety se Česká republika spolu s dalšími devíti evropskými zeměmi staly členy Evropské unie. Ačkoliv si Česká republika oficiálně připomene svůj vstup do Evropské unie 1. května, Úřad vlády ČR ve spolupráci se Zastoupením Evropské komise v ČR a dalšími partnery přichystaly řadu akcí, které budou probíhat po celé jaro. Europe Day is observed annually on May 05, 2014. There are two separate designations of Europe Day: The Council of Europe's day was established in 1949, while the European Union's (EU) day celebrates the day the EU's predecessor was proposed in 1950. For the EU, the day is also known as Schuman Day, comme morating the historical declaration by French foreign minister Robert Schuman.

Journal of Metallomics and Nanotechnologies

Druhé číslo právě vyšlo
Časopis Journal of Metallomics and Nanotechnologies vychází pouze elektronicky, čtvrtletně. Jeho obsahové zaměření je v oblastí nano-biochemie, nanotechonologie, biomedicína a nanomedicína. Časopis vychází bez regionálních mutací v českém, slovenském a anglickém jazyce. Vydavatel: Laboratoř metalomiky a nanotechnologií Mendelova univerzita v Brně, Zemědělská 1, 613 00, Brno, Česká republika http://web2.mendelu.cz/af_239_nanotech/J_Met_Nano/index.html

Zprávy z výzkumu/ Scientific Reports

Orion’s First Crew Module Complete
X-rays From A Young Supernova Remnant NASA’s first completed Orion crew module sits atop its service module at the Neil Armstrong Operations and Checkout Facility at Kennedy Space Center in Florida. The crew and service module will be transferred together on Wednesday to another facility for fueling, before moving again for the installation of the launch abort system. At that point, the spacecraft will be complete and ready to stack on top of the Delta IV Heavy rocket that will carry it into space on its first flight in December. For that flight, Exploration Flight Test-1, Orion will travel 3,600 miles above the Earth – farther than any spacecraft built to carry people has traveled in more than 40 years – and return home at speeds of 20,000 miles per hour, while enduring temperatures near 4,000 degrees Fahrenheit.
Flying Through an Aurora
W3 Star-forming Region European Space Agency astronaut Alexander Gerst posted this photograph taken from the International Space Station to social media on Aug. 29, 2014, writing, "words can't describe how it feels flying through an #aurora. I wouldn't even know where to begin…." Crewmembers on the space station photograph the Earth from their unique point of view located 200 miles above the surface. Photographs record how the planet is changing over time, from human-caused changes like urban growth and reservoir construction, to natural dynamic events such as hurricanes, floods and volcanic eruptions. Crewmembers have been photographing Earth from space since the early Mercury missions beginning in 1961. The continuous images taken from the space station ensure this record remains unbroken.

W3 Star-forming Region On Tuesday, Sept. 9 aboard the space station, cosmonaut Max Suraev of Roscosmos takes the helm when Expedition 40 Commander Steve Swanson hands over control during a Change of Command Ceremony at 5:15 p.m. EDT. Suraev will lead Expedition 41 and stay in orbit until November with Gerst and NASA astronaut Reid Wiseman. Soyuz Commander Alexander Skvortsov, Swanson and Flight Engineer Oleg Artemyev will complete their mission Wednesday, Sept. 10 at 7:01 p.m. when they undock in their Soyuz TMA-12M spacecraft from the Poisk docking compartment for a parachute-assisted landing on the steppe of Kazakhstan a little less than 3.5 hours later. Expedition 40 Soyuz TMA-12M Landing Ground support personnel are seen at the landing site after the Soyuz TMA-12M spacecraft landed with Expedition 40 Commander Steve Swanson of NASA, and Flight Engineers Alexander Skvortsov and Oleg Artemyev of the Russian Federal Space Agency (Roscosmos) near the town of Zhezkazgan, Kazakhstan on Thursday, Sept. 11, 2014. Swanson, Skvortsov and Artemyev returned to Earth after more than five months onboard the International Space Station where they served as members of the Expedition 39 and 40 crews.
Space Station Expedition 40 Crew Returns to Earth, Lands Safely in Kazakhstan
W3 Star-forming Region Three crew members from the International Space Station (ISS) returned to Earth Wednesday after 169 days of science and technology research in space, including a record 82 hours of research in a single week, which happened in July. A trio of International Space Station crew members returned to Earth and landed in Kazakhstan at 10:23 p.m. EDT on Sept. 10, 2014 (8:23 a.m., Sept. 11, in local time) after spending 167 days aboard the orbital laboratory. Seen left to right, Oleg Artemyev and Alexander Skvortsov of the Russian Federal Space Agency (Roscosmos) and NASA’s Steve Swanson were examined by medical personnel after being removed from their Russian Soyuz spacecraft. Image Credit: NASA Television

W3 Star-forming Region Expedition 40 Commander Steve Swanson of NASA and Flight Engineers Alexander Skvortsov and Oleg Artemyev of the Russian Federal Space Agency (Roscosmos) touched down southeast of the remote town of Dzhezkazgan in Kazakhstan at 10:23 p.m. EDT Wednesday, Sept. 10 (8:23 a.m., Sept. 11, in Dzhezkazgan). During their time aboard the space station, the crew members participated in a variety of research focusing on Earth remote sensing, human behavior and performance and studies of bone and muscle physiology. One of several key research focus areas during Expedition 40 was human health management for long duration space travel as NASA and Roscosmos prepare for two crew members to spend one year aboard the orbiting laboratory in 2015. During their time on the station, the crew members orbited Earth more than 2,700 times, traveled more than 71.7 million miles and welcomed five cargo spacecraft. Two Russian ISS Progress cargo spacecraft docked to the station bringing tons of supplies in April and July. The fifth and final European Space Agency (ESA) Automated Transfer Vehicle also launched to the station in July with the spacecraft bearing the name of Belgian physicist Georges Lemaitre, who is considered the father of the big-bang theory. SpaceX launched a Dragon cargo spacecraft to the station in April, the company's third of at least 12 planned commercial resupply missions. In July, Orbital Sciences’ Cygnus spacecraft completed its third of at least eight resupply missions scheduled through 2016 under NASA's Commercial Resupply Services contract. During his time on the complex, Swanson ventured outside the confines of the space station for a spacewalk to replace a backup computer relay box that unexpectedly failed. Skvortsov and Artemyev conducted two spacewalks during Expedition 40, totaling 12 hours and 34 minutes. The space station is more than a scientific research platform. It also serves as a test bed to demonstrate new technology. Even routine tasks, such as monitoring and operating the carbon dioxide removal system, provides valuable data for next-generation life support systems. Carbon dioxide removal from the pressurized compartments of the station proved to work differently in space than predicted by ground tests. The crew also saw the arrival of the Haptics-1 experiment, part of an effort to develop technology that would allow an astronaut in orbit to control a robot as it explores its target, such as an asteroid or Mars, during future human exploration missions. Having completed his third space station mission, Swanson now has spent a total of 196 days in space. Skvortsov has accumulated 345 days in space on two flights, and Artemyev accrued 169 days in space on his first mission. Expedition 41 now is operating aboard the station with Max Suraev of Roscosmos in command. Suraev and his crewmates, Flight Engineers Reid Wiseman of NASA and Alexander Gerst of ESA, will tend to the station as a three-person crew until the arrival in two weeks of three new crew members: Barry Wilmore of NASA and Alexander Samokutyaev and Elena Serova of Roscosmos. Wilmore, Samokutyaev and Serova are scheduled to launch from Kazakhstan Thursday, Sept. 25 NASA Astronaut Steve Swanson Returns to Earth Expedition 40 Commander Steve Swanson of NASA rests in a chair outside the Soyuz Capsule just minutes after he and Flight Engineers Alexander Skvortsov and Oleg Artemyev of the Russian Federal Space Agency (Roscosmos), landed in their Soyuz TMA-12M capsule in a remote area near the town of Zhezkazgan, Kazakhstan on Thursday, Sept. 11, 2014. Swanson, Skvortsov and Artemyev returned to Earth after more than five months onboard the International Space Station where they served as members of the Expedition 39 and 40 crews.
Satellite View of Newborn Atlantic Tropical Depression 6
W3 Star-forming Region The sixth tropical depression of the Atlantic Ocean Hurricane Season formed in the Eastern Atlantic Ocean and NOAA's GOES-East satellite captured it. A visible image of Tropical Depression 6 was taken by NOAA's GOES-East satellite at 7:45 a.m. EDT on September 11 as it developed. The image was created by NASA/NOAA's GOES Project at the NASA Goddard Space Flight Center in Greenbelt, Maryland. In addition to using GOES imagery and data from other NOAA and NASA satellites, The National Hurricane Center also uses measurements from the Advanced Scatterometer or ASCAT instrument that flies aboard the EUMETSAT METOP satellite. Forecaster Beven at the National Hurricane Center noted "Satellite imagery and a recent ASCAT-B overpass indicate that the low pressure area over the eastern Atlantic has a well-defined circulation and organized convective banding near the center." At 11 a.m. EDT Tropical Depression Six had maximum sustained winds near 35 mph (55 kph) and the depression could become a tropical storm later in the day. The center of Tropical Depression Six was located near latitude 16.2 north and longitude 37.1 west, about 870 miles (1,400 km) west of the Cape Verde Islands. The depression is moving toward the northwest near 13 mph (20 kph) and is expected to move northwest or west-northwest is expected during the next couple of days. The estimated minimum central pressure is 1007 millibars.
Changes of the human gut microbiome induced by a fermented milk product
The gut microbiota (GM) consists of resident commensals and transient microbes conveyed by the diet but little is known about the role of the latter on GM homeostasis. Here we show, by a conjunction of quantitative metagenomics, in silico genome reconstruction and metabolic modeling, that consumption of a fermented milk product containing dairy starters and Bifidobacterium animalis potentiates colonic short chain fatty acids production and decreases abundance of a pathobiont Bilophila wadsworthia compared to a milk product in subjects with irritable bowel syndrome (IBS, n = 28). The GM changes parallel improvement of IBS state, suggesting a role of the fermented milk bacteria in gut homeostasis. Our data challenge the view that microbes ingested with food have little impact on the human GM functioning and rather provide support for beneficial health effects.
Insights into the electrocatalysis of nitrobenzene using chemically-modified carbon nanotube electrodes
W3 Star-forming Region The electrochemical behavior of nitrobenzene and its derivatives at chemically-functionalized multi-wall carbon nanotubes (MWNTs) modified electrodes was studied. Experimental results showed that hydroxyl-containing MWNTs exhibited the highest electrocatalytic activity among the used MWNTs because of its weak capacitive features and oxygen-containing functional groups. The cycle voltammetrys of nitrobenzene derivatives on the MWNTs modified electrodes can be easily tuned by changing the substituted groups of nitrobenzene. Based on the experimental data, the electrochemical reaction mechanisms of nitrobenzene and its derivatives on the MWNTs modified electrodes have been discussed and analyzed.
Diagnostic value of circulating free DNA for the detection of EGFR mutation status in NSCLC: a systematic review and meta-analysis
W3 Star-forming Region Epidermal growth factor receptor (EGFR) mutation is a reliable and sensitive biomarker for EGFR-TKI therapy in non-small-cell lung cancer (NSCLC). However, detection of EGFR mutation in tissues has obvious limitations. Circulating free DNA (cfDNA) has been reported as an alternative approach for the detection of EGFR mutations. This systematic review and meta-analysis was designed to assess the diagnostic performance of cfDNA, compared with tissues. True-positive (TP), false-positive (FP), false-negative (FN), and true-negative (TN) values were extracted or calculated for each study. Pooled sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), and diagnostic odds ratio (DOR) were calculated. A summary receiver operating characteristic curve (SROC) and area under curve (AUC) were used to evaluate the overall diagnostic performance. 20 eligible studies involving 2012 cases were included in this meta-analysis. The pooled sensitivity, specificity, PLR, NLR, andDORwere 0.674 (95%CI: 0.517–0.800), 0.935 (95%CI: 0.888–0.963), 10.307 (95%CI: 6.167–17.227), 0.348 (95%CI: 0.226–0.537), and 29.582 (95%CI: 4.582–60.012), respectively. The AUC was 0.93 (95% CI: 0.90–0.95). The meta-analysis suggests that detection of EGFR mutation by cfDNA is of adequate diagnostic accuracy and cfDNA analysis could be a promising screening test for NSCLC.
Soyuz TMA-12M Departs from Station
W3 Star-forming Region ISS041-E-000044 (10 Sept. 2014) --- The Soyuz TMA-12M spacecraft departs from the International Space Station and heads toward a landing in a remote area near the town of Zhezkazgan, Kazakhstan. NASA astronaut Steve Swanson, Expedition 40 commander; Russian cosmonaut Alexander Skvortsov, Soyuz commander and flight engineer; and Russian cosmonaut Oleg Artemyev, flight engineer, are returning from more than five months aboard the space station where they served as members of the Expedition 39 and 40 crews. Landing occurred at 10:23 p.m. (EDT), Sept. 10, 2014 (8:23 a.m., Sept. 11, Kazakh time).
Expedition 42 Crew Portrait
W3 Star-forming Region ISS042-S-002 (9 July 2014) --- Expedition 42 crew members take a break from training at NASA’s Johnson Space Center to pose for a crew portrait. Pictured on the front row are NASA astronauts Barry Wilmore (left), commander; and Terry Virts, flight engineer. Pictured from the left (back row) are Russian cosmonauts Elena Serova, Alexander Samoukutyaev and Anton Shkaplerov and European Space Agency astronaut Samantha Cristoforetti, all flight engineers. Photo credit: NASA/Bill Stafford
Expedition 39/40 Crew Departs From Station in Soyuz
W3 Star-forming Region ISS041-E-000005 (10 Sept. 2014) --- The Soyuz TMA-12M spacecraft departs from the International Space Station and heads toward a landing in a remote area near the town of Zhezkazgan, Kazakhstan. NASA astronaut Steve Swanson, Expedition 40 commander; Russian cosmonaut Alexander Skvortsov, Soyuz commander and flight engineer; and Russian cosmonaut Oleg Artemyev, flight engineer, are returning from more than five months aboard the space station where they served as members of the Expedition 39 and 40 crews. Landing occurred at 10:23 p.m. (EDT), Sept. 10, 2014 (8:23 a.m., Sept. 11, Kazakh time).


Journal of Metallomics and Nanotechnologie
laboratorní časopis
- informace pro autory

Upozornění pro cestující týkající se výskytu horečky způsobené virem EBOLA - pdf

Technické podrobnosti a úpravy v informačním systému – I
Prof. Ing. René Kizek, Ph.D.
úterý 16. 09. 2014, od 14:00 – 18:00 h

Spektrofotometrické stadium interakce doxorubicinu/ethidium bromidu s N-myc fragmentem
Ing. Lukáš Nejdl
18. 09. 2014, od 15:00

Praktický kurz monitorování vybraných markerů u nádorových prostatických buněk pomocí real-time PCR
RNDr. Jan Balvan
18. 09. 2014, od 10:00 – 18:00 h

Monitorování vlastností červených a bílých krvinek vystavených působení kovových prvků a sloučenin prostřednictvím průtokové cytometrie
Ing. Dr. Branislav Ruttkay-Nedecký
pátek 19. 09. 2014, od 14:00

Flurescenční mikroskop – základy použití
Ing. et Ing. David Hynek, Ph.D.
19. 09. 2014, 14:00

Modifikace mikro a nanočástic vazebnými komponenty
Kristýna Číhalová
19. 09. 2014, od 12:00

Virus purification - ultracentrifugation
Ing. Bc. Petr Michálek
pátek 19. 09. 2014, od 12:00

FIA-ED: optimization of method for electrochemical study of doxorubicin
Mgr. Roman Guráň
pátek 19. 09. 2014, od 16:00

Flow Injection Analysis with Electrochemical Detection for Rapid Identification of Platinum-Based Cytostatics and Platinum Chlorides in Water
Mgr. Bc. Markéta Komínková
pátek 19. 09. 2014, od 17:00

Obhajovací prezentace práce Biofyzikální studium malých RNA
Kristýna Šmerková
19. 09. 2014, od 12:00

Functional traits of tropical trees
Anna Vidomcová
pátek 19. 9. 2014, od 14:00 h

Corvinus University of Budapest (CUB)
September 18-20, 2014


Nanocon 2014
6. mezinárodní konference
5. - 7. listopadu 2014 - Hotel Voroněž I, Brno, Česká republika, EU

Journal of Metallomics and Nanotechnologies

Prototyp funkční vzorek

Způsob detekce virových hemaglutininů pomocí anorganických nanočástic ukotvených na chromatografickém papíru

Komplex biopolymerní látky s nanočásticemi selenu a antibiotickými léčivy s antibakteriálním účinkem

Informační systém pro vážení


Monitoring of the Surface Modification of Nanoparticles by Electrochemical Measurements Using Scanning Electrochemical Microscope

The effect of silver ions and silver nanoparticles on Staphylococcus aureus

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